Monday, July 30, 2012

Drug-resistant HIV 'Africa rising'

Researchers discovered in the part of the drug-resistant HIV significantly sub-Saharan Africa almost 10 years of antiretroviral therapy (ART) before, since its launch has increased.


Yesterday was published in the Lancet study (23 July), call the emergency action researchers improve the surveillance of the prevalence of resistance to the arts through a survey on business population HIV-positive people.


"Wishes to understand the trends in resistance monitoring program, strategy please incorporate is very important because treatment program to notify you must change the regimen of our need to," said the researcher, SciDev.Net in London University United Kingdom, Ravindra gupta, lead author.


Using data on more than 26000 HIV-positive people in Asia, Latin America, and sub-Saharan Africa.


Sub-Saharan Africa Government started rolling in the first nationwide treatment program launch art in January of the year in 2002, Botswana. Since then, developed national economies similar treatment program.


However, researchers from Nigeria, Switzerland, United Kingdom, United States of America, identified the past decade a significant rise in the art resistance sub-Saharan Africa region.


For example, has increased yearly 29% resistance now had reached 7.4% eight years resistance after the East African art roll-out art. Drug-resistant roll-out in South Africa 14% are increasing every year 3% rate after six years.


Researchers increase due to resistance to the agent mainly used the art resistance by binding to part of the HIV virus, non-nucleoside of reverse transcriptase inhibitor (NNRTI ) in virus reproduction function block art. Part of simple genetic mutation of NNRTI binding after the treatment of the disorder in the NNRTIs virus outbreak — even one mutation can bestow the high resistance in the patient.


Researcher says that the barriers to increase the capacity of the monitoring program, such as the high cost of.


Told SciDev.Net Gupta said: "because it is the problem for the drug money more would be great, but using money from the existing program, and apparently means less people.


"On the other hand, we compared the cost to much smaller treat surveillance programs cost estimation of art and life of people. ?


Underfunding also challenged, Gupta said: "no ability WHO are certified to queue the is labs, provide the certification itself. Will be good if each laboratory specialized testing of their own country. ?


Developed a solution, and easier to test the resistance of the Professor of the London public health, international health and tropical medicine, and Alison grant, HIV experts said rural communities: arid Central Research Institute testing using, for example, blood spots, and stored in the filter paper to be carried.


She said that to sustain the extraordinary success of the art rollout, we find the way to make the monitoring of, and should happen.


The abstract link

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