Kathmandu, researchers are parasitical visceral leishmaniasis, drug-resistant, developed a method to detect the most serious form of the infection faster and more reliable.
Leishmaniasis, sent by a parasite that is spread by the neglected diseases, Laois Mania donovani, sandfly. Parasites infect to the abdomen can be fatal if untreated, visceral leishmaniasis is known as the third of the skin and mucous membranes (VL),.
VL 162, 100 and 313600 if the little province is reported each year in South Asia occupy 80% of the India of Northern Bihar, Eastern and Central Nepal, Bangladesh, burden.
Infection is most heavy burden in Bangladesh-specific, Brazil, India, Nepal, Sudan and in 60 countries.
Analysed the Laois Mania strains isolated from patients with 50 in recent EU funded research Germany, India, Nepal, Switzerland, United Kingdom, India, Nepal, including researchers from the authority of the Belgium resistance.
Long drugs containing sodium stiboglucante VL is antimony or 'antimonials' primary form of treatment in recent years some strains becomes resistant, according to survey published its findings infectious diseases Journal last month ( 6/29 ).
Cultured and infected cells identify the test resistance at the lab generates results sometimes wrong, it takes at least five days, contains a standard way to handle this.
New method builds on the base array Leishmania gene recently completed genome. Polymerase chain reaction ' or use a technique called PCR to amplify the gene sequences to detect mutations in genes of resistance to the antimonials and multiplication.
"Only one not only easy and fast testing, reliability of" explained the Tropical Medicine Institute of research by lead author Manu Vanaerschot, Antwerp ( ITG), Belgium.
"This work more efficient removal strategy VL currently held in India, Nepal, Bangladesh, programme for Kala-Azar through contribution" for VL is removal by 2015, in 2005, see the campaigns by the three countries, Vanaerschot said.
New method is not a diagnostic tool and parasites of the author of the study, Jean-Claude Dujardin epidemiological description with molecules at the head of the ITG. Aims to improve monitoring regional level
Yang simplifies the testing of field applications of researchers working with Raj Bhattarai, b. p. Koirala Dhahran in Health Science Institute laboratory coordinator said.
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